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姓名:葛亚东 |
职称:副教授 |
电话:0553-3869297 |
邮箱:geyd@ahnu.edu.cn |
◆ 主要学习工作经历
· 2002、2005、2010年 安徽师范大学分别获学士、硕士、博士学位
· 2002年至今 安徽师范大学生命科学学院工作,历任讲师、副教授
· 2012年 美国堪萨斯州立大学博士后研究
· 2018年11月-2025年3月 任校国际交流合作处副处长、兼国际教育学院副院长
◆ 主要研究内容
· 蛋白质酶学与功能演化
· 蓝藻关键代谢酶基因功能
◆ 主要研究课题
· 国家自然科学基金项目:不同克隆轮虫形态可塑性差异及其生态学与分子生物学机制研究(32070463),2021-2024,第一参与人
· 国家自然科学基金项目:铜绿微囊藻苹果酸脱氢酶的酶学及辅酶特异性转换研究(31300006),2014-2016,主持
· 安徽省自然科学基金项目:铜绿微囊藻苹果酸脱氢酶的结构与辅酶进化关系研究(1208085QC52),2012-2014,主持
· 安徽省高等学校优秀青年人才基金项目:链霉菌基因组文库构建及工业用酶基因的筛选与改造(2009SQRZ030),2009-2011,主持
◆ 主要研究成果
一、代表性论文(*表示通讯作者)
· Yali Ge, Jialin Zhu, Yu Ren, Xiaojie Wu, Bo Zhou, Yifan Wu, Yadong Ge*. Trans-generational morphological trait plasticity in parthenogenetic offspring of two Brachionus dorcas morphotypes induced by Asplanchna kairomones. Ecology and Evolution, 2026, 16:e72956.
· Ge Yadong, Wu Yifan, Zhou Bo, Wu Xiaojie, Ren Yu, Zhu Jialin and Ge Yali*. A Novel Dual Coenzyme Specificity and Thermostable Malate Dehydrogenase Identified in the Cyanobacterium Microcystis aeruginosa PCC7806. International Journal Of Molecular Sciences. 2025, 26, 10313.
· Ge Yadong, Wu Minglong , Lei Jinxi, Yu Ren, Zhu Jialin, Wu Yifan, Xi Yilong* and Ge Yali*. Life-history and trans-generational morphological trait plasticity in parthenogenetic offspring of two Brachionus dorcas morphotypes induced by temperature. Ecological Frontiers, 2025, 45(5):1461-1468.
· Ge Yadong*, Guo Yitian, Jiang Lulu, Wang Huihui, Hou Shaolin, Su Fengzhi. Enzymatic characterization and coenzyme specificity conversion of a novel dimeric malate dehydrogenase from Bacillus subtilis. The Protein Journal, 2023, 42(1): 14-23.
· Ge Yadong*, Jiang Lulu, Hou Shaolin, Su Fengzhi, Wang Peng, Zhang gen*. Heteroexpression and biochemical characterization of thermostable citrate synthase from the cyanobacteria Anabaena sp. PCC7120. Protein expression and purification, 2020, 168:e105565.
· Ge Yadong*, Hou Shaolin, Jiang Lulu, Su Fengzhi, Wang Peng. Expression and characterization of a thermostable citrate synthase from Microcystis aeruginosa PCC7806. FEMS microbiology letters. 2019, 366(19):e1-7.
· Ge Yadong, Cao Zhengyu, Song Ping, Zhu Guoping*. Identification and characterization of a novel citrate synthase from Streptomyces diastaticus No.7 strain M1033. Biotechnology and Applied Biochemistry, 2015, 62(3):300-308.
· Ge Yadong, Song Ping, Wang Peng, Zhu Guoping*. Alteration of coenzyme specificity of malate dehydrogenase from Streptomyces coelicolor A3(2). Genetics and Molecular Research, 2014, 13(3):5758-5766.
· Ge Yadong, Cao Zhengyu, Wang Zongda, Chen Lulu, Zhu Youming, Zhu Guoping*. Identification and biochemical characterization of a thermostable malate dehydrogenase from the mesophile Streptomyces coelicolor A3(2). Bioscience Biotechnology and Biochemistry, 2010, 74 (11):2194-2201.
· Li Xue, Wang Peng, Ge Yadong, Wang Wen, Abbas Abdulla, Zhu Guoping*. NADP+-specific isocitrate dehydrogenase from oleaginous yeast Yarrowia lipolytica CLIB122: biochemical characterization and coenzyme sites evaluation. Applied Biochemistry Biotechnology, 2013, 171:403-416.
· Zhao Hanjun, Wang Peng, Huang Enqi, Ge Yadong, Zhu Guoping*. Physiologic roles of soluble pyridine nucleotide transhydrogenase in Escherichia coli as determined by homologous recombination. Annals of Microbiology, 2008, 58(2):275-280.
· 葛亚东, 葛雅丽, 王鹏, 朱国萍*. 分子生物学国家级双语教学示范课程的实践与思考. 中国细胞生物学学报, 2013, 35(8): 1251-1254.
· 葛亚东, 潘蔚, 汪诘, 朱国萍*. 柠檬酸合酶的分子生物学研究进展. 生物学杂志, 2010, 27(3): 59-62.
二、授权专利
· 葛亚东,苏凤智,侯少林,蒋璐璐,朱国萍。一种热稳定性苹果酸脱氢酶基因的构建方法、编码蛋白及其应用,中国发明专利号:ZL 2019 1 0900263.0,2021年。
三、编写教材
· 参编高等师范院校生命科学系列教材《分子生物学》(第三版,ISBN 978-7-03-077221-3,科学出版社,2024年6月)“第六章:翻译”。