
| 姓名:高如心 职称:特聘副教授 电话:15624961109 邮箱:ruxin1958@163.com |
◆ 主要学习工作经历
●2023-09至今 安徽师范大学,特聘副教授
●2018-09 至 2023-07, 中国农业大学, 博士
●2014-09 至 2018-06, 中国农业大学, 学士
◆ 主要社会兼职
●无
◆ 主要研究内容
1.代谢通路关键基因功能及代谢性疾病治疗的分子机制探索
2.食品功能因子功效评价与生物活性机制研究
3.天然产物靶向递送体系的功效验证及体内代谢机制研究
4.食品功能因子相关的功能性食品及特殊医学用途配方食品开发
◆ 主要研究课题
1. 国家自然科学基金委员会, 青年科学基金项目(C类)[原青年科学基金项目], 82400672, 非酒精性脂 肪肝病中脂肪酸合酶(FASN)的乳酸化修饰变化和调控机制探索, 2025-01-01 至 2027-12-31, 30万元, 在研, 主持
◆ 主要研究成果
一、代表性论文及论著:
1.Ruxin Gao#; Yue Li#; Zhimeng Xu; Feng Zhang; Jia Xu; Yanzhou Hu; Jingya Yin; Kun Yang; Lei Sun; Qi Wang; Xiaoyun He; Kunlun Huang ; Mitochondrial pyruvate carrier 1 regulates fatty acid synthase lactylation and mediates treatment of nonalcoholic fatty liver disease, Hepatology, 2023, 2023(78): 1800-1815
2.Xu Chen#; Xiaoyun He#; Ruxin Gao#; Xinyue Lan; Longjiao Zhu; Keren Chen; Yanzhou Hu; Kunlun Huang; Wentao Xu ; Aptamer-Functionalized Binary-Drug Delivery System for Synergetic Obesity Therapy, ACS Nano, 2021, 16(1): 1036-1050
3.Yanzhou Hu; Jia Xu; Ruxin Gao; Ye Xu; Bingxin Huangfu; Charles Asakiya; Xianghui Huang; Feng Zhang; Kunlun Huang; Xiaoyun He; Yunbo Luo ; Diallyl Trisulfide Prevents Adipogenesis and Lipogenesis by Regulating the Transcriptional Activation Function of KLF15 on PPARγ to Ameliorate Obesity, Molecular Nutrition & Food Research, 2022, 2022(66): 2200173-2200173
4.Xiaoyun He; Haoyu Li; Ruxin Gao; Chuanhai Zhang; Fei Liang; Yao Sheng; Shujuan Zheng; Jia Xu; Wentao Xu; Kunlun Huang ; Mulberry leaf aqueous extract ameliorates blood glucose and enhances energy expenditure in obese C57BL/6J mice, Journal of Functional Foods, 2019, 63:103505
5. Feng Zhang; Minglan Yang; Jia Xu; Yanzhou Hu; Ruxin Gao; Kunlun Huang; Xiaoyun He ; Coreopsis tinctoria and Its Flavonoids Ameliorate Hyperglycemia in Obese Mice Induced by High-Fat Diet, Nutrients, 2022, 14(6): 1160-1160
二、专利:
无
三、主要获奖情况:
无