◆ 主要学习工作经历

●   2018年南京理工大学博士学位

●   2018年7月至今在安徽师范大学生命科学学院工作

◆ 主要社会兼职

●   中国细胞生物学会会员

●   安徽省解剖学会学会会员

●   Journal of Ethnopharmacology等期刊审稿人

◆ 主要研究内容

主要从事细胞代谢调控、靶标发现与功能验证；中药及天然药物防治重大疾病药理机制研究。

◆ 主要研究课题

1. 安徽省自然科学基金青年项目，基于小胶质细胞极化研究TSG对大鼠脑缺血再灌注损伤的保护机制，1908085QH342，2019-2021，主持。

◆ 主要研究成果

一、 代表性论文及论著：

1. Li, M., Lu, W., Meng, Y., Zhang, W., Wang, F., Sun, L., Xu, Y., 2022. Tetrahydroxy Stilbene Glucoside Alleviates Ischemic Stroke by Regulating Conformation-Dependent Intracellular Distribution of PKM2 for M2 Macrophage Polarization. J. Agric. Food Chem. 70: 15449-15463.

2. Yang, L., Li, M.(共一), Shen, M., Bu, S., Zhu, B., He, F., Zhang, X., Gao, X., Xiao, J., 2022. Chromosome-level genome assembly and annotation of the native Chinese wild blueberry Vaccinium bracteatum. Fruit Research 2(1), 1-14.

3. Li, T.X., Liang, J.X., Liu, L.L., Shi, F.C., Jia, X.W., Li, M.H. (共通), Xu, C.P., 2021. Novel kojic acid derivatives with anti-inflammatory effects from Aspergillus versicolor. Fitoterapia 154, 105027.

4. Li, M.-H., Feng, X., Chen, C., Ruan, L.-Y., Xing, Y.-X., Chen, L.-Y., Zhong, G.-J., Wang, J.-S., 2019. Hepatoprotection of Herpetospermum caudigerum Wall. against CCl₄-induced liver fibrosis on rats. J. Ethnopharmacol. 229, 1-14.

5. Ruan, L.Y., Li, M.H. (共一), Xing, Y.X., Hong, W., Chen, C., Chen, J.F., Xu, H., Zhao, W.L., Wang, J.S., 2019. Hepatotoxicity and hepatoprotection of Polygonum multiflorum Thund. as two sides of the same biological coin. J. Ethnopharmacol. 230, 81-94.

6. Li, M.-H., Ruan, L.-Y., Chen, C., Xing, Y.-X., Hong, W., Du, R.-H., Wang, J.-S., 2018. Protective effects of Polygonum multiflorum on ischemic stroke rat model analysed by 1H NMR metabolic profiling. J. Pharm. Biomed. Anal. 155, 91-103.

7. Feng, X., Li, M.-H. (共一), Xia, J., Ba, D.J.D., Ruan, L.-Y., Xing, Y.-X., Chen, C., Wang, J.-S., Zhong, G.-J., 2018. Tibetan Medical Formula Shi-Wei-Gan-Ning-Pill Protects Against Carbon Tetrachloride-Induced Liver Fibrosis–An NMR-Based Metabolic Profiling. Front. Pharmacol. 9: 965.

8. Xing, Y.-X., Li, M.-H. (共一), Tao, L., Ruan, L.-Y., Hong, W., Chen, C., Zhao, W.-L., Xu, H., Chen, J.-F., Wang, J.-S., 2018. Anti-Cancer Effects of Emodin on HepG2 Cells as Revealed by 1H NMR Based Metabolic Profiling. J. Proteome Res. 17(5), 1943-1952.

9. Li, M.-H., Du, H.-Z., Kong, G.-J., Liu, L.-B., Li, X.-X., Lin, S.-S., Jia, A.-Q., Yuan, S.-T., Sun, L., Wang, J.-S., 2017. Nuclear Magnetic Resonance-Based Metabolomics Approach to Evaluate the Prevention Effect of Camellia nitidissima Chi on Colitis-Associated Carcinogenesis. Front. Pharmacol. 8, 447.

10. Li, M.-H., Ruan, L.-Y., Zhou, J.-W., Fu, Y.-H., Jiang, L., Zhao, H., Wang, J.-S., 2017. Metabolic profiling of goldfish (Carassius auratis) after long-term glyphosate-based herbicide exposure. Aquat. Toxicol. 188, 159-169.

11. Li, M.-H., Xu, H.-D., Liu, Y., Chen, T., Jiang, L., Fu, Y.-H., Wang, J.-S., 2016. Multi-tissue metabolic responses of goldfish (Carassius auratus) exposed to glyphosate-based herbicide. Toxicology Research 5(4), 1039-1052.

12. Li, M.-H., Ruan, L.-Y., Liu, Y., Xu, H.-D., Chen, T., Fu, Y.-H., Jiang, L., Wang, J.-S., 2015. Insight into biological system responses in goldfish (Carassius auratus) to multiple doses of avermectin exposure by integrated 1H NMR-based metabolomics. Toxicology Research 4(5), 1374-1388.

13. Li, M., Wang, J., Lu, Z., Wei, D., Yang, M., Kong, L., 2014. NMR-based metabolomics approach to study the toxicity of lambda-cyhalothrin to goldfish (Carassius auratus). Aquat. Toxicol. 146, 82-92.

14. Lu, Z.-G., Li, M.-H. (共一), Wang, J.-S., Wei, D.-D., Liu, Q.-W., Kong, L.-Y., 2014. Developmental toxicity and neurotoxicity of two matrine-type alkaloids, matrine and sophocarpine, in zebrafish (Danio rerio) embryos/larvae. Reprod. Toxicol. 47, 33-41.