◆ 主要学习工作经历

●   1990.9-1994.6 扬州大学农学院  本科

●   1995.9-1998.6 南京农业大学植保学院 硕士研究生

●   2001.9-2005.12南京农业大学植保学院 在职博士研究生

●   1998.8-2001.7 江苏省农科院植保所 研究实习员

●   2001.8-2005.7江苏省农科院植保所 助理研究员

●   2005.8-2009.7江苏省农科院植保所 副研究员

●   2009.9-2010.8英国牛津大学 国家公派访问学者

●   2009.8-2017.11江苏省农科院植保所 研究员

●   2017.12-至今 江苏省农科院植保所 研究员/副所长

◆ 主要社会兼职

●   江苏省昆虫学会秘书长

●   中国昆虫学会理事

◆ 主要研究内容

研究方向为害虫生物防治。以水稻和蔬菜重大害虫为靶标对象，在深入研究害虫与杀虫微生物协同进化关系等基础上，研发微生物杀虫剂新产品并进行产业化开发。

◆ 主要研究课题

1.        国家自然基金面上项目32172410：爪哇虫草菌对褐飞虱体内共生菌Arsenophonus与Wolbachia调控作用及其机制 (2022-2025)  58万元

2.        国家自然基金面上项目31972265：褐飞虱体内共生菌Arsenophonus与Wolbachia的互作效应及其机理 (2020-2023)  57万元

3.        国家自然基金面上项目31672027：稻飞虱体内共生菌Wolbachia的保护功能及机理(2017-2020)  60万元

4.        国家科技支撑计划：水稻重大病虫害防控技术研究与集成示范（2012-2016）880万元

◆ 主要研究成果

一、           代表性论文及论著：

1.        Zhao D#, Ni X#, Zhang Z, Niu H, Qiu, Guo H*. Bt protein hasten entomopathogenic fungi-induced death of nontarget pest whitefly by suppressing protective symbionts. Science of the Total Environment , 2022, 853, 158588.  http://dx.doi.org/10.1016/j.scitotenv.2022.158588（#为共同第一作者，*为通讯作者）

2.        Guo H, Qu Y, Sun S, Zhang K, Zhang Z, Zhao D, Niu H, Liu X, Fang J, Hoffmann A. Antiviral effect of the cotton plant‑derived gossypol against tomato yellow leaf curl virus. Journal of Pest Science, 2022, https://doi.org/10.1007/s10340-022-01551-y

3.        Jiang HQ, Ding Y, Zhao DX, Liu XD*, Guo HF*.  First discovery of Arsenophonus infection in spiders, the predators of insect pests. Journal  of Applied Entomology, 2022, https://doi.org/10.1111/jen.213017（*为通讯作者）

4.        Niu H, Sun Y, Zhang Z, Zhao D, Wang N, Wang L, Guo H*.  The endophytic bacterial entomopathogen Serratia marcescens promotes plant growth and improves resistance against Nilaparvata lugens in rice. Microbiological Research, 2022, https://doi.org/10.1016/j.micres.2021.126956（*为通讯作者）

5.        Guo H, Wang N, Niu H, Zhao D, Zhang Z. Interaction of Arsenophonus with Wolbachia in Nilaparvata lugens. BMC Ecology and Evolution, 2021, https://doi.org/10.1186/s12862-021-01766-0

6.        Sun S, Wang Z, Zhang Z, Hoffmann AA, Guo H*. The roles of entomopathogenic fungal infection of viruliferous whiteflies in controlling tomato yellow leaf curl virus. Biological Control , 2021, https://doi.org/10.1016/j.biocontrol.2021.104552（*为通讯作者）

7.        Li YT, Liu XD, Wang N, Zhang YL, Hoffmann AA and Guo HF*. Background-dependent Wolbachia-mediated insecticide resistance in Laodelphax striatellus. Environmental Microbiology, 2020,  DOI: 10.1111/1462-2920.14974 22（7）: 2653-2663（*为通讯作者）

8.        Zhao DX, Zhang ZC, Niu HT and Guo HF*. Win by quantity: a striking Rickettsia-bias symbiont community revealed by seasonal tracking in the whitefly Bemisia tabaci. Microbial Ecology，2020， https://doi.org/10.1007/s00248-020-01607-5（*为通讯作者）

9.        Li YT,  Liu XD, Guo HF *. Population Dynamics of Wolbachia in Laodelphax striatellus (Fallén)  under successive stress of antibiotics. Current Microbiology, 2020，https://doi.org/10.1007/s00284-019-01762-0

10.     Liu XD, Guo HF. Correlation between insecticide resistance and endosymboints Wolbachia and Rickettsia. Current Opinion in Insect Science， 2019, 33:84–90

11.     Zhao D, Zhang Z, Niu Ho and Guo H*.  Selective and stable elimination of endosymbionts from multiply infected whitefly Bemisia tabaci (Gennadius) by feeding on a cotton plant cultured in antibiotic solutions. Insect Science, 2019, doi:10.1111/1744-7917.12703（*为通讯作者）

12.     Guo H, Qu Y. Improvement on natural enemies of Bemisia tabaci using extracts of Agrimonia pilosa. Journal of Economic Entomology, 2019, 112(4):1581-1586. doi:10.1093/jee/toz074（*为通讯作者）

13.     Zhao D, Hoffmann A, Zhang Z, Niu H and Guo H*. Interaction between facultative symbionts Hamiltonella and Cardinium in Bemisia tabaci: cooperation or conflict? Journal of Economic Entomology. 2018, DOI:10. 1093/jee/toy261（*为通讯作者）

14.     Li Y, Liu X*, Huifang Guo*. Variations in endosymbiont infection between buprofezin-resistant and susceptible strains of Laodelphax striatellus (Fallén). Current Microbiology 2018,75(6)  DOI: 10.1007/s00284-018-1436-x

15.     Niu H, Xiao L, Wang N, Liu B, Wang L, Guo H*. Synergistic and additive interactions of Serratia marcescens S-JS1 to the chemical insecticides for controlling Nilaparvata lugens Stål. Journal of Economic Entomology 2018,111(2):823-828. doi: 10.1093/jee/tox348. （*为通讯作者）

16.     Li Y, Zhang Y, Liu X*, and Guo H*. Does Resistance to buprofezin improve heat and cold tolerance of Laodelphax striatellus (Hemiptera: Delphacidae)? Environmental Entomology, 2017, 46(4): 988–994（*为通讯作者）

17.     Zhang Y, Han Y, Yang Q, Wang L, He P, Liu Z, Guo H*, Fang J*. Resistance to cycloxaprid in Laodelphax striatellus is associated with altered expression of nicotinic acetylcholine receptor subunits. Pest Management Science, 2017, 74（4）：837-843. DOI:10.1002/ps.4757（*为通讯作者）

18.     Niu H, Liu B, Li Y, Guo H*. Identification of a bacterium isolated from the diseased brown planthopper and determination of its insecticidal activity. Biocontrol Science and Technology, 2015, 26(2):217-226（*为通讯作者）

19.     Guo H, Qu Y, Liu X, Zhong W, Fang J.^.  Female-biased symbiont and tomato yellow leaf curl virus infection in Bemisia tabaci. Plos one, 10.1371/journal.pone.0084538

20.     Guo H, Fang J, Zhong W, Liu B. Interactions between Meteorus pulchricornis and Spodoptera exigua multiple nucleopolyhedrovirus. Journal of Insect Science. 13:12. Available online: http://www.insectscience.org/13.12

21.     Guo H, Fang Jichao, Liu Baosheng, Wang Jieping, Zhong Wanfang, Wang Fanghao. Enhancement of the biological activity of nucleopolyhedrovirus through disruption of the peritrophic matrix of insect larvae by chlorfluazuron. Pest Management Science, 2007, 63: 68-74

22.     Guo H, Fang J, Wang J, Zhong W, Liu B. Interaction of Xestia c-nigrum granulovirus with Spodoptera litura nucleopolyhedrovirus and peritrophic matrix in Spodoptera litura. Journal of Economic Entomology, 2007, 100(1)：20-25

二、专利：

1.        Guo H. et al. Use of Agrimonia pilosa extract in preparation of drug for removing plant virus in tomato plants  PCT美国授权 US 10,813,361 B2（2020年授权）

2.        郭慧芳，方继朝等. 一种利用植物源提取物提高害虫寄生蜂耐药性的方法ZL201310291678.5

3.        郭慧芳，方继朝等. 一种利用斑痣悬茧蜂提高甜菜夜蛾核型多角体病毒侵染力的方法ZL200710191566.7

4.        郭慧芳，方继朝等.  仙鹤草提取物在制备提高寄生蜂寄生能力的药物中的应用 ZL200810156162.9

5.        郭慧芳等. 仙鹤草提取物在制备增强蜘蛛捕食功能的药物中的应用 ZL200810156163.3

三、主要获奖情况：

1.        国家科技进步二等奖（第5完成人）：长江中下游稻飞虱暴发机制及可持续防控技术（2015）

2.        江苏省科学技术一等奖（第7完成人）：高产水稻飞虱的区域暴发机制与综合防控技术（2013）

3.        江苏省科技进步一等奖（第4完成人）：水稻螟虫的灾变规律与可持续控制技术（2005）

4.        江苏省科技成果转化一等奖（第5完成人）：吡虫啉超高效控制害虫的无公害技术转化（2003）