◆ 主要学习工作经历

●学习经历

●2010.09-2013.12，中科院昆明植物研究所/云南大学，理学博士，导师：杨祝良/赵之伟

●2002.09-2005.12，武汉大学，生命科学学院，理学硕士，导师：谢谢志雄/沈萍

●1998.09-2002.07，南昌大学，生命科学与食品工程学院，理学学士

●工作经历

●2020.10-至今    安徽师范大学 生命科学学院 教授

●2016.09-2020.08  安徽师范大学 生命科学学院 副教授

●2018.11-2019.11  美国罗格斯大学 访问学者

●2014.07-2016.08  中国科学院 微生物研究所 博士后

●2005.08-2014.06  红河学院 生命科学与技术学院 讲师/副教授

◆ 主要社会兼职

●中国微生物学会会员；Applied and Environmental Microbiology,  International Journal of Biological Macromolecules, Microbiology Spetrum, Frontier in Microbiology, Archaea, Marine Biotechnology, PLoS One, Int J Syst Evol Microbiol,《微生物学报》、《微生物学通报》等微生物学领域国内外期刊审稿人。

◆ 主要研究内容

主要从事：（1）嗜盐古菌胞外蛋白酶参与的微生物相互作用机制；（2）极端环境微生物资源的发掘与利用；（3）嗜盐古菌病毒与宿主的相互作用。

◆ 主要研究课题

1. 云南省真菌多样性与绿色发展重点实验室基金课题，2024，主持

2. 安徽省自然科学基金面上项目， 2208085MC39，2022.01-2024.12，主持

3. 微生物资源前期开发国家重点实验室开放课题，SKLMR-20220702，2022.7-2024.6，主持

4. 江南大学工业生物技术教育部重点实验室开放课题，KLIB-KF201704，2018-2020，主持

5. 安徽高校自然科学基金重点项目，KJ2017A318，2017-2019，主持

6. 安徽省高校优秀青年人才资助计划，gxyqZD201711，2017-2019，主持

7. 安徽省引进高层次人才资助计划，2017-2019，主持

8. 国家自然科学基金项目，31460003，2015.1-2.18.14，主持

9. 红河学院中青年学术技术带头人后备人才项目，2012，主持

◆ 主要研究成果

一、代表性论文及论著(*通讯作者)：

Chen S*, Dai Y, Ke J, Luo Y, Wang C, Hao Y, Zhang A, Han J, Xiang H. Halocin H4 is activated through cleavage by halolysin HlyR4. Appl Environ Microbiol. 2024, Accept.

Chen G, Yang A, Wang J, Ke L, Chen S, Li W. Effects of the synergistic treatments of arbuscular mycorrhizal fungi and trehalose on adaptability to salt stress in tomato seedlings. Microbiol Spectr. 2024, 23:e0340423.

Hong T, Ke J, Chen L, Hao Y, Lu P, Chen S*. Genomic, Physiological, Biochemical, and Phenotypic Evidences Reveal a New Species, Halomicroarcula salaria sp. nov. Curr Microbiol. 2024 Jan 23;81(3):71.

Zhang K, Zhou H, Ke J, Feng H, Lu C, Chen S*, Liu A. Biodegradation of phthalic acid esters (PAEs) by Janthinobacterium sp. strain E1 under stress conditions. J Gen Appl Microbiol. 2024, doi: 10.2323/jgam.2023.12.002.

Hong T, Pan R, Ke J, Luo Y, Hao Y, Chen L, Tu D, Dai Y, Chen T, Chen S*. Expression, purification, and enzymatic characterization of an extracellular protease from Halococcus salifodinae. Braz J Microbiol. 2023, 54(4):2689-2703.

Chen L, Hong T, Wu Z, Song W, Chen SX*, Liu Y, Shen L. Genomic analyses reveal a low-temperature adapted clade in Halorubrum, a widespread haloarchaeon across global hypersaline environments. BMC Genomics. 2023, 24(1):508.

Zhang S, Chen F, Ke J, Hao Y, Pan R, Hong T, Dai Y, Chen S*. Hly176B, a low-salt tolerant halolysin from the haloarchaeon Haloarchaeobius sp. FL176. World J Microbiol Biotechnol. 2023, 39(7):189.

Hu R, Wu L, Cheng Q, Chen S, Shen T, Lan D, Ma Y, Wang Y. Structural variations and phospholipid binding characteristics of Streptomyces klenkii phospholipase D at the lipid-water interface. LWT - Food Science and Technology. 2023, 179:114672.

张申奥, 陈飞龙, 陈博, 苏亦鸣, 陈绍兴*. 常见盐渍食品中嗜盐微生物分布及其胞外酶活. 食品与生物技术学报, 2023, 42(8):38-45.

Tu D, Ke J, Luo Y, Hong T, Sun S, Han J, Chen S*. Microbial community structure and shift pattern of industry brine after a long-term static storage in closed tank. Front Microbiol. 2022, 13:975271.

Chen S, Tu D, Hong T, Luo Y, Shen L, Ren P, Lu P, Chen X. Genomic features of a new head-tail halovirus VOLN27B infecting a Halorubrum strain. Gene, 2022, 841:146766.

Wang R, Chen F, Wang J, Liu A, Ke L, Wan F, Chen S*. Halorhabdus amylolytica sp. nov. and Halorhabdus salina sp. nov., isolated from hypersaline environments. Int J Syst Evol Microbiol, 2022, 72(4). doi: 10.1099/ijsem.0.005346.

苏亦鸣, 陈飞龙, 张申奥, 陈绍兴. 盐渍海带盐中可培养嗜盐古菌多样性、胞外酶活及拮抗作用探究. 微生物学杂志, 2022, 5:19-30.

Chen S, Dai Y, Liu J, Zhang S, Chen F, Jin F, Ruan P, Li L, Chen X. 2021. VOLN27B: A New Head-Tailed Halovirus Isolated from an Underground Salt Crystal and Infecting Halorubrum. Archaea, 2021, 2021: 8271899.

Chen S, Sun S, Wang R, Feng H, Xiang H. Haloferax mediterranei halolysin R4 confers antagonistic and defensive capabilities. Appl Environ Microbiol, 2021, 87:e02889-20.

王锐，陈绍兴*. 嗜盐古菌几种常见胞外酶研究进展. 微生物学通报, 2021, 48(3):830-841.

Chen F, Xu Y, Sun S, Shi X, Liu A, Chen S*. Halomicroarcula amylolytica sp. nov., a novel halophilic archaeon isolated from a salt mine. Int J Syst Evol Microbiol, 2020, 70(9):4978-4985.

Chen S, Xu Y, Helfant L. Geographical Isolation, Buried Depth, and Physicochemical Traits Drive the Variation of Species Diversity and Prokaryotic Community in Three Typical Hypersaline Environments. Microorganisms, 2020, 8(1):120.

Bouillet S, Wu T, Chen S, Stock AM, Gao R. Structural asymmetry does not indicate hemiphosphorylation in the bacterial histidine kinase CpxA. J Biol Chem, 2020, 295(23):8106-8117.

Chen S, Sun S, Xu Y, Chen F, Liu J. Halobellus captivus sp. nov., an extremely halophilic archaeon isolated from a subterranean salt mine. Antonie van Leeuwenhoek, 2020, 113(2):221‐231.

Chen S, Xu Y, Sun S, Liu J, Chen F. Halomicrococcus hydrotolerans gen. nov., sp. nov., an extremely halophilic archaeon isolated from a subterranean salt deposit. Int J Syst Evol Microbiol, 2020, 70(8):4425-4431.

Chen S, Sun S, Korfanty GA, Liu J, Xiang H. A Halocin Promotes DNA Uptake in Haloferax mediterranei. Front Microbiol, 2019, 10:1960.

Sun S, Chen F, Xu Y, Liu J, Chen S*. Halorubrum amylolyticum sp. nov., a novel halophilic archaeon isolated from a salt mine. Antonie van Leeuwenhoek, 2019, 112(12):1849‐1861.

陈礼楠, 李峰, 孙思琪, 许瑶, 陈绍兴*. 安徽定远盐矿可培养嗜盐微生物多样性. 微生物学通报, 2019, 46(9): 2186−2197

Chen S, Xu Y, Sun S, Chen F, Liu J. Halalkalicoccus subterraneus sp. nov., an extremely halophilic archaeon isolated from a subterranean halite deposit. Antonie van Leeuwenhoek, 2019, 112(7):1067‐1075.

Xu Y, Lv J, Xie C, Sun S, Ke L, Chen S*. Halorubrum glutamatedens sp. nov., a Halophilic Archaeon Isolated from a Rock Salt. Curr Microbiol, 2019, 76(1):52-56.

Chen S, Siqi Sun, Yao Xu, Hong-Can Liu. Halococcus salsus sp. nov., a novel halophilic archaeon isolated from rock salt. Int J Syst Evol Microbiol, 2018, 68(12):3754-3759.

Chen S, Sun S, Xu Y, Lv J, Chen L, Liu L. Halorubrum depositum sp. nov., a novel halophilic archaeon isolated from a salt deposit. Curr Microbiol, 2018, 75(6):677-683.

Chen S, Xu Y, Ke LX. Halorubrum trueperi sp. nov., a halophilic archaeon isolated from a salt mine. Int J Syst Evol Microbiol, 2017, 67(5):1564-1570.

Chen S, He J, Zhang J, Xu Ym, Huang J, Ke LX. Halorubrum salsamenti sp. nov., a novel halophilic archaeon isolated from a brine of salt mine. Curr Microbiol, 2017, 74(11):1358-1364.

Chen S, Xu Y, Liu HC, Yang AN, Ke LX. Halobaculum roseum sp. nov., isolated from underground salt deposits. Int J Syst Evol Microbiol, 2017, 67(4):818-823.

Chen S, Xu Y, Zheng C, Ke LX. Marivibrio halodurans gen. nov., sp. nov., a marine bacterium in the family Rhodospirillaceae isolated from underground rock salt. Int J Syst Evol Microbiol, 2017, 67(10):4266-4271.

Chen S, Liu HC, Zhou J, Xiang H. Haloparvum sedimenti gen. nov., sp. nov., a member of the family Haloferacaceae. Int J Syst Evol Microbiol, 2016, 66(6):2327-2334.

Chen S, Liu HC, Zhou J, Xiang H. Halorubrum pallidum sp. nov., an extremely halophilic archaeon isolated from a subterranean rock salt. Int J Syst Evol Microbiol, 2016, 66(8):2980-2986.

Chen S, Liu HC, Zhao D, Yang J, Zhou J, Xiang H. Halorubrum yunnanense sp. nov., isolated from a subterranean salt mine in Yunnan, China. Int J Syst Evol Microbiol, 2015, 65(12):4526-4532.

Chen S, Wang C, Xiang H. Sequence analysis and minimal replicon determination of a new haloarchaeal plasmid pHF2 isolated from Haloferax sp. strain Q22. Plasmid, 2015, 83(1):1-7.

Chen S, Wang C, Xu JP, Yang ZL. Molecular characterization of pHRDV1, a new virus-like mobile genetic element closely related to pleomorphic viruses in haloarchaea. Extremophiles, 2014, 18(2):195-206.

Chen S, Tulloss RE, Liu Y, Feng B, Zhao Z, Yang ZL. Lateral gene transfer occurring in haloarchaea: an interpretative imitation study. World J Microbiol Biotechnol, 2012, 28(9):2913-2918.

◆ 学生获奖

●研究生

研究生国家奖学金：孙思琪（2020）、陈飞龙（2021）、涂德梅（2023）

安徽省品学兼优毕业生：孙思琪（2020）

安科生物奖学金：许瑶（2018，2019）、孙思琪（2019）、代永沛（2022）

九川奖学金：许瑶（2020）、孙思琪（2020）、王锐（2021）

臻格生物奖学金：王锐（2022）

●本科生

全国大学生生命科学竞赛：陈礼楠（二等奖）、吕金亭、张申奥（三等奖）

安徽省大学生生命科学竞赛：张申奥、潘如如、查海薇（三等奖）

安徽师范大学第十届大学生科研论文大赛：苏亦鸣（二等奖）、张申奥（三等奖）、潘如如（优秀奖）

（热忱欢迎对微生物学有浓厚兴趣的优秀研究生或本科生加入我们课题组！）