·   姓名:龚仁敏

·   职称:教授

·   电话:0553-3869297

·   邮箱:rmgong.nju@163.com

◆主要学习工作经历

…………………………………………………………

·   1986-1989  无锡轻工业学院(现江南大学),硕士研究生

·   2001-2004  南京大学生命科学学院,博士研究生

·   2005-2007  江南大学生物工程学院,博士后

·   1980-1986  芜湖市地方病防治站,干部

·   1989-    安徽师范大学生命科学学院,讲师、副教授、教授

◆主要社会兼职

…………………………………………………………

·   安徽省生物化学及分子生物学学会理事

·   安徽省科学技术奖评委

·   安徽省食品安全咨询专家。

◆主要研究内容

…………………………………………………………

·   纳米生物医药及肿瘤靶向治疗

·   口服蛋白质药物载体

·   酶抑制剂开发应用

◆主要研究课题

…………………………………………………………

·   基于廉价植物材料的阳离子吸附剂的制备及应用,江苏省博士后科研资助计划(0502031c),主持人,2006.1-2007.12

·   新型高分子螯合吸附剂的研制和应用,中国博士后科学基金(20060390960),主持人,2006.1-2007.12

·   柠檬酸酯化秸秆可降解阳离子吸附剂制备及应用,安徽高校省级自然科学研究一般项目 (2006KJ182B),主持人,2006.1-2007.12

·   秸秆制备羧基型纤维素类阳离子吸附剂的研究,安徽高校省级自然科学研究重点项目 (KJ2008A045),主持人,2008.1-2009.12

·   普鲁蓝糖靶向输药自组装脂质体的制备,安徽师范大学重点科研项目(2009xzd06),主持人,2009.1-2010.12

·   新型天然载体共价固定化脂肪酶及其应用,食品科学与技术国家重点实验室开放课题(SKLF-KF-201101),主持人,2012.1-2013.12

·   藻毒素降解菌细胞生长与降解酶合成的耦合关系及细胞固定化的研究,安徽省自然科学基金(1208085MC42 ),主持人,2012.1-2013.12

·   微囊藻毒素降解菌细胞生长、相关基因转录、酶合成的关系及细胞固定化的研究,教育部高等学校博士学科点(博导类)专项科研基金(20123424110004 ),主持人,2013.1-2015.12

◆主要研究成果

…………………………………………………………

1、代表性论文(20篇以内,*号为通讯作者):

·   Mingming Song, Liangping Li, Yue Zhang, Kuanmin Chen, Hui Wang, Renmin Gong*, Carboxymethyl-β-cyclodextrin grafted chitosan nanoparticles as oral delivery carrier of protein drugs, React. Funct. Polym., 2017. 117: 10-15. (工程技术2)

·   Liangping Li, Ruisong Tao, Mingming Song, Yue Zhang, Hui Wang, Kuanmin Chen, Renmin Gong*, Fabrication of self-assembled folate-biotin-quaternized starch nanoparticles as co-carrier of doxorubicin and siRNA, J. Biomater. Appl., 2017. 32: 587-597.

·   Ming Wang, Meiling Huang, Jianting Wang, Mingquan Ye, Yan Deng, Honghao Li, Wensi Qian, Bolin Zhu, Yao Zhang?, Renmin Gong*, Facile one-pot synthesis of self-assembled folate-biotin-pullulan nanoparticles for targeted intracellular anticancer drug delivery, J. Nanomater., 2016. 2016: 1-10.

·   Jianting Wang, Ming Wang, Mingming Zheng, Qiong Guo, Yafan WangHeqing Wang, Xiangrong Xie, Fenghong Huang?, Renmin Gong*, Folate mediated self-assembled phytosterol-alginate nanoparticles for targeted intracellular anticancer drug delivery, Colloid. Surface. B, 2015. 129: 63-70. (生物科学2) 

·   Suoju He, Miaomiao Dai, Jun Zhu, Bo Jiang, Renmin Gong*, Preparation and characterization of lipase immobilized on reversibly soluble-insoluble N-(2-carboxylbenzoyl) chitosan, J. Sol-gel Sci. Techn., 2012. 63: 519-525.

·   Renmin Gong, Chengcheng Li, Shengxue Zhu, Yinye Zhang, Yan Du, Jihong Jiang?, A novel pH-sensitive hydrogel based on dual crosslinked alginate/N-α-glutaric acid chitosan for oral delivery of protein, Carbohyd. Polym., 2011. 85: 869-874. (应用化学1)

·   Renmin Gong, Yan Jiang, Wenkai Cai, Ke Zhang, Bo Yuan, Jihong Jiang?, Enhanced sorption of bisphenol A on α-ketoglutaric acid-modified chitosan resins by hydrophobic sorption of hemimicelles, Desalination, 2010. 258: 54-58.(水资源1)

·   Renmin Gong*, Min Feng, Jiajing Zhao, Wenkai Cai, Lingling Liu, Functionalization of sawdust with monosodium glutamate for enhancing its malachite green removal capacity, Bioresour. Technol., 2009. 100: 975-978.(工程技术1)

·   Renmin Gong*, Shoujun Ni, Jiajing Zhao, Na Li, Epichlorohydrin and aspartic acid incorporated into sawdust and application as sorbent for methylene blue, Wood Sci. Technol., 2009. 43: 183-193. (林学2)

·   Renmin Gong*, Youbin Jin, Jin Sun, Keding Zhong, Preparation and utilization of rice straw bearing carboxyl groups for removal of basic dyes from aqueous solution. Dyes Pigments, 2008. 76: 519-524. (材料科学:纺织1)

·   Renmin Gong, Jin Sun, Demin Zhang, Keding Zhong, Guoping Zhu?, Kinetics and thermodynamics of basic dye sorption on phosphoric acid esterifying soybean hull with solid phase preparation technique, Bioresour. Technol., 2008. 99: 4510-4514.(工程技术1)

·   Renmin Gong*, Keding Zhong, Yun Hu, Jian Chen, Guoping Zhu, Thermochemical esterifying citric acid onto lignocellulose for enhancing methylene blue sorption capacity of rice straw, J. Environ. Manage., 2008. 88: 875-880. (环境科学2)

·   Renmin Gong*, Shengxue Zhu, Demin Zhang, Jian Chen, Shoujun Ni, Rui Guan, Adsorption behavior of cationic dyes on citric acid esterifying wheat straw: kinetic and thermodynamic profile, Desalination, 2008. 230: 220-228. (水资源1)

·   Renmin Gong*, Youbin Jin, Jian Chen, Yun Hu, Jin Sun, Removal basic dyes from aqueous solution by sorption on phosphoric acid modified rice straw. Dyes Pigments, 2007. 73: 332-337. (材料科学:纺织1)

·   Renmin Gong*, Xiaoping Zhang, Huijun Liu, Yingzhi Sun, Birong Liu, Uptake of cationic dyes from aqueous solution by biosorption onto granular kohlrabi peel. Bioresour. Technol., 2007. 98: 1319-1323.(工程技术1)

·   Renmin Gong*, Youbin Jin, Fayang Chen, Jian Chen, Zhili Liu, Enhanced malachite green removal from aqueous solution by citric acid modified rice straw. J. Hazard. Mater., 2006. 137: 865-870.(工程技术1)

·   Renmin Gong*, Yi Ding, Mei Li, Chao Yang, Huijun Liu, Yingzhi Sun, Utilization of powdered peanut hull as biosorbent for removal of anionic dyes from aqueous solution. Dyes Pigments, 2005. 64: 187-192. (材料科学:纺织1)

·   Renmin Gong, Yi Ding, Huijun Liu, Qiuyi Chen, Zhili Liu?, Lead biosorption and desorption by intact and pretreated Spirulina maxima biomass. Chemosphere, 2005. 58: 125-130(环境科学2)

·   Renmin Gong*, Yingzhi Sun, Jian Chen, Huijun Liu, Chao Yang, Effect of chemical modification on dye adsorption capacity of peanut hull. Dyes Pigments, 2005. 67: 175-181.(材料科学:纺织1)

·   Renmin Gong*, Mei Li, Chao Yang, Yingzhi Sun, Jian Chen, Removal of cationic dyes from aqueous solution by adsorption on peanut hull. J. Hazard. Mater., 2005. 121: 247-250.(工程技术1)

2、专利:

·   龚仁敏,刘志礼,曹德华,靳友彬,国家发明专利:一种阳离子吸附剂的制备方法及应用,专利号:ZL 2005100404858(已授权)

·   龚仁敏,梁晶晶,冯敏,蔡文开,国家发明专利:一种改性木屑的制备及使用方法,专利号:ZL 200810244757.X(已授权)

·   龚仁敏,李程程,张银叶,何所惧,国家发明专利:一种口服蛋白类药物的制备方法,专利号:ZL 201010588005.2(已授权)

·   龚仁敏,郭琼,王建婷,国家发明专利:一种叶酸靶向的纳米粒,其用途以及合成和检测方法,专利号:ZL 201310674971.X(已授权)

·   龚仁敏,王建婷,汪茗,黄美玲,国家发明专利:一种叶酸修饰胆固醇疏水改性海藻酸钠自组装纳米粒及其制备方法和应用,专利号:ZL 201410127916.3(已授权)